INDIA-BORN Parag Agrawal’s appointment this week as the new CEO of Twitter suggests the company has picked engineering as its top priority and reflects a tacit endorsement by the board to double its annual revenue by 2023, even if investors were not so sure.
Jack Dorsey announced on Monday (29) that he is stepping down from his role as chief executive officer of Twitter Inc and chief technology officer Agrawal will now lead the company.
Twitter shares surged nearly 10 per cent after the announcement and closed down 2.7 per cent.
The CEO change is effective immediately and Dorsey will remain on the board until his term expires at the 2022 annual shareholder meeting, the company said.
In an email to employees on Monday, Dorsey said he chose to step down due to the strength of Agrawal's leadership, the naming of Salesforce chief operating officer Bret Taylor as the new chairman of the board and his confidence in the "ambition and potential" of Twitter's employees.
"I'm really sad ... yet really happy," he wrote. "There aren't many companies that get to this level," adding that his move to step down "was my decision and I own it."
In an email to employees, Agrawal said, “We recently updated our strategy to hit ambitious goals, and I believe that strategy to be bold and right. But our critical challenge is how we work to execute against it and deliver results.”
Over the past year, Twitter has fought to end years-long criticism that it has been slow to introduce new features for its 211 million daily users and was losing ground to social media rivals like Instagram and TikTok.
Under Dorsey's leadership, Twitter acquired email newsletter service Revue and launched Spaces, a feature that lets users host or listen to live audio conversations.
The company also rolled out advertising improvements to help brands find Twitter users likely to be interested in their product, a key component of the company's goal to double annual revenue by 2023.
Agrawal has helped lead Twitter's work on incorporating cryptocurrencies and blockchain technologies into the company and also pursue its long-term ambition to rebuild how social media companies operate.
He has been a key figure in Bluesky, a Twitter-funded organisation that is seeking to build a "decentralized" common standard for social media companies. Such a standard would allow different social platforms to operate on the same technology and let users post content across the services, for instance.
Bluesky's work will likely take years to complete, Dorsey has said.
For now, investors are hoping Agrawal's technical prowess will help Twitter's advertising "engine" grow, said analysts from Baird Equity Research in a note on Monday.
Twitter earns the majority of its revenue from selling advertising on its website and app. But its ability to offer highly targeted advertising to drive product sales has lagged far behind larger rival Facebook, advertising experts have said.
The company previously said it sought to grow its highly targeted advertising segment to 50 per cent of its business - it currently constitutes just 15 per cent.
As investors digested the news, the market likely realized Agrawal's "mountain to scale" to reach the company's revenue targets and felt "some disappointment that a Twitter outsider hasn’t been brought in to offer fresh ideas," said Susannah Streeter, an analyst at Hargreaves Lansdown.
Dorsey, who co-founded Twitter in 2006, is leaving after overseeing the launch of new ways to create content through newsletters or audio conversations while simultaneously serving as CEO of his payments processing company Square Inc.
Dorsey will now focus on leading Square and other pursuits such as philanthropy, a source familiar with the matter told Reuters.
The company's board has been preparing for Dorsey's departure since last year, the source said.
Uterine cancer cases and deaths are projected to rise significantly in the US by 2050.
Black women are expected to experience the highest increase in incidence-based mortality.
A new model predicts incidence rising to 86.9 cases per 100,000 for Black women and 74.2 for White women.
Researchers stress the urgent need for improved prevention and early detection strategies.
Sharp increase in uterine cancer predicted over next three decades
Uterine cancer, currently the fourth most commonly diagnosed cancer among women in the United States, is projected to see a substantial rise in both cases and deaths by 2050, particularly among Black women. A new study led by researchers at Columbia University warns of worsening racial disparities in outcomes if preventative measures are not introduced.
This year alone, around 69,120 new cases of uterine cancer and nearly 14,000 deaths are expected in the United States. However, projections by the Columbia University research team, published in Cancer Epidemiology, Biomarkers & Prevention, indicate a significant increase in both incidence and mortality over the next 30 years.
Black women to face disproportionate increase in mortality
The study found that Black women already experience double the mortality rate from uterine cancer compared to women from other racial and ethnic backgrounds. Using a predictive model, researchers estimated that this gap will widen dramatically by 2050.
The incidence-based mortality rate among Black women is expected to rise from 14.1 per 100,000 in 2018 to 27.9 per 100,000 by 2050. In contrast, for White women, the rate will increase from 6.1 per 100,000 to 11.2 per 100,000 in the same period.
The incidence rate is also projected to rise to 86.9 cases per 100,000 in Black women and 74.2 cases per 100,000 in White women by 2050, compared to 56.8 and 57.7, respectively, in 2018.
About the study model
The projections were developed using the Columbia University Uterine Cancer Model (CU-UTMO), a state-transition microsimulation tool designed as part of the National Cancer Institute’s Cancer Intervention and Surveillance Modeling Network (CISNET).
The model simulates the disease trajectory based on age (18–84), race (Black and White), tumour type (endometrioid or nonendometrioid), stage at diagnosis, and birth cohort from 1910 onwards. It was validated using 2018 data and showed a strong fit to actual incidence and mortality statistics.
Lead author Dr Jason D. Wright, the Sol Goldman Professor of Gynaecologic Oncology at Columbia University, explained:
“There are likely a number of factors that are associated with the increased burden of uterine cancer in Black women. They more commonly have aggressive types of uterine cancer, face delayed diagnosis resulting in later-stage disease at diagnosis, and there are often delays in their treatment.”
More aggressive tumour types in Black women
The model also highlighted that while endometrioid tumours, a less aggressive form, are projected to increase in both Black and White women, the rate of nonendometrioid tumours, which have a poorer prognosis, will rise considerably in Black women alone.
These trends point to an urgent need for improved public health interventions aimed at early diagnosis and treatment, as well as research into tailored approaches for high-risk groups.
Potential for prevention and screening
In a stress test of the model, researchers incorporated hypothetical screening methods capable of detecting uterine cancer and precancerous changes before clinical diagnosis. The analysis found that such interventions could lead to significant reductions in cancer incidence, lasting up to 15 years in White women and 16 years in Black women, if introduced at the age of 55.
Dr Wright commented on the implications of the test:
“The stress testing suggests that if there was an effective screening test, we may be able to substantially reduce the burden of disease. While there is presently no screening or prevention that is routinely used for uterine cancer, we are currently examining the potential impact of integrating screening into practice.”
Call for action
With cases and deaths from uterine cancer projected to climb, the researchers conclude that immediate steps must be taken to develop and implement primary and secondary prevention strategies. Without intervention, the burden of uterine cancer, particularly among Black women, is expected to grow significantly, posing serious public health challenges in the decades ahead.
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Deepika Padukone to be honoured with a Hollywood Walk of Fame star in 2026 under the Motion Pictures category.
She is the first Indian actress to receive the recognition, announced by the Hollywood Chamber of Commerce.
The Class of 2026 also includes Emily Blunt, Rami Malek, Timothée Chalamet and Miley Cyrus.
Deepika expressed her gratitude on Instagram, calling the moment “Gratitude…”.
Deepika Padukone has been named among the 2026 honourees for the Hollywood Walk of Fame, becoming the first Indian actress to receive the distinction. The announcement, made during a live event hosted by the Hollywood Chamber of Commerce, places her alongside a global line-up of actors, musicians, and broadcasters to be celebrated with their own stars on Hollywood Boulevard next year.
Deepika Padukone to get Hollywood Walk of Fame star Getty Images
Hollywood Walk of Fame committee selects Deepika for Motion Pictures category
Deepika’s name was included in the Motion Pictures category, joining a list of 35 individuals from across entertainment. This year’s selection includes actors Emily Blunt, Rachel McAdams, Rami Malek, and Timothée Chalamet, among others. Past inductee Eugenio Derbez and radio host Richard Blade revealed the names via livestream. The committee evaluated hundreds of entries before selecting honourees based on their artistic contributions, public appeal, and philanthropic work.
Jury Member Deepika Padukone attend the Palme D'or winner press conference Getty Images
Deepika Padukone’s international journey and Hollywood debut
Padukone’s inclusion, in fact, reflects her global appeal. After rising to fame in Bollywood, she entered Hollywood with the 2017 action film xXx: Return of Xander Cage, co-starring Vin Diesel. Since then, she has represented Indian cinema on international platforms such as Cannes and the Met Gala. Earlier this year, she featured in Kalki 2898 AD, one of India’s highest-grossing films, and is currently attached to Atlee’s next project alongside Allu Arjun.
Deepika Padukone honoured with Hollywood star in 2026 Getty Images
No, celebrities can’t buy their way into the Walk of Fame
With each announcement, speculation swirls online about whether stars purchase this honour. However, Walk of Fame officials clarified that selections are made through a transparent process. Anyone can submit a nomination, but it must be supported by the artist and meet strict criteria, including a minimum of five years in the industry and verifiable public impact. A sponsor later pays a fee, currently between £59,000 (₹6.2 crore) and £66,000 (₹7 crore), used for maintenance, not for purchase of the star itself.
Deepika Padukone becomes Walk of Fame honouree in 2026Getty Images
Not the first Indian name, but a major milestone for Indian cinema
While Deepika’s recognition marks a landmark for Indian women in cinema, she is not the first Indian to appear on the Walk. That honour goes to Sabu Dastagir, a Mysore-born actor who became a Hollywood sensation in the 1930s and received his star in 1960. Nevertheless, Padukone’s inclusion underscores a new era of global visibility for Indian actors.
Last week, I had the privilege of speaking at the Circles of Connections event hosted by the Society of Jainism and Entrepreneurship at Imperial College London. The event was organised by Yash Shah and Hrutika S., and generously sponsored by Koolesh Shah and the London Town Group, with support from Nikhil Shah, Priyanka Mehta, and Ambika Mehta.
The experience reminded me that leadership isn’t just about vision or results — it’s about how you show up, and why you do what you do.
Hatul Shah
During my talk, I shared stories from my journey in business and reflected on how the principles of Jainism have quietly shaped the way I lead. I’m not a strict Jain, but I deeply respect the values passed down to me by my grandfather and father. Three in particular — Ahimsa (non-violence), Satya (truth and transparency), and Dana (charity through entrepreneurial spirit) — have become anchors in how I make decisions, lead teams, build culture, and, most importantly, how I treat people.
These values don’t just influence your actions. They define your identity — and over time, they shape how others experience your leadership.
It was energising to connect with students, emerging entrepreneurs, and peers — each on their own journey, yet all driven by purpose and values.
Leadership and legacy are not separate tracks. The strongest leaders carry both — and pass them forward.
(This reflection was originally shared on LinkedIn by Hatul Shah, CEO of Sigma Pharmaceuticals.)
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